Korean J Dermatol.  2010 Sep;48(9):776-779.

A Case of Subcutaneous Pyogenic Granuloma, and a Review of the Literature

Affiliations
  • 1Department of Dermatology, School of Medicine, Kyunghee University, Seoul, Korea. nikim@khmc.or.kr

Abstract

Pyogenic granuloma (lobular capillary hemangioma) is a very common benign vascular lesion that frequently appears as a red to purple colored papule or polypoid mass. Any cutaneous or mucous membrane surface may be affected, they are rarely found intravascular or subcutaneous area. A 67-year-old female presented with a single, 0.5x0.5 cm sized movable subcutanous nodule on the right arm. A biopsy specimen showed multilobulated angiomatous nodule consisted of proliferative capillaries with fibrous septum in the subcutaneous layer. The tumor cells were positive for CD31, CD34, vimentin and smooth muscle actin. The lesion was excised and pyogenic granuloma was given as diagnosis by histopathological evaluation. The Subcutaneous type of pyogenic granuloma is rare but it should be part of the differential diagnosis of solitary nodule of extremities.

Keyword

Lobular capillary hemangioma; Subcutaneous pyogenic granuloma

MeSH Terms

Actins
Aged
Arm
Biopsy
Capillaries
Diagnosis, Differential
Extremities
Female
Granuloma, Pyogenic
Humans
Mucous Membrane
Muscle, Smooth
Vimentin
Actins
Vimentin
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