Korean J Dermatol.  2004 Apr;42(4):500-502.

A Case of Allergic Contact Dermatitis Due to Topical Minoxidil

• Kang KS
• Lee BH
• Han HJ
• Park CW
• Lee CH

Abstract

Minoxidil (2, 6-diamino-4-piperidinopyrimidine 1-oxide) is a systemic antihypertensive agent, the topical application of which has been shown to produce hair growth. Topical minoxidil solution (5% minoxidil, propylene glycol, alcohol, water) has generally been well-tolerated, but allergic contact dermatitis has been reported. When allergic contact dermatitis to minoxidil solution is suspected, evaluation of ingredients of minoxidil solution should be performed because allergic contact dermatitis due to propylene glycol in minoxidil solution has been frequently reported. A 34-year-old male presents with a diffuse erythematous patch on the scalp. He has applied minoxidil solution for 7 days due to androgenic alopecia. A Patch test with Korean standard series and the ingredients of used topical agents showed positive reactions to 1%, 2% and 5% minoxidil solution.

Keyword

Allergic contact dermatitis; Minoxidil

MeSH Terms

Adult
Alopecia
Dermatitis, Allergic Contact*
Hair
Humans
Male
Minoxidil*
Patch Tests
Propylene Glycol
Scalp
Minoxidil
Propylene Glycol