Korean J Dermatol.  2004 Apr;42(4):460-463.

A Case of Pyoderma Gangrenosum Associated with Autoimmune Chronic Active Hepatitis

• Hong SB
• Kang IJ
• Lee JI
• Kim NI

Abstract

Pyoderma gangrenosum (PG) is an inflammatory ulcerative condition of unclear etiology. In more than 50% of cases, lesions occur in association with an underlying systemic disorder-most notably; inflammatory bowel disease (IBD), rheumatoid arthritis, or a hematologic abnormality. Here, we report a rare case of pyoderma gangrenosum associated with autoimmune chronic active hepatitis. A 34-year-old woman presented with a 2-month history of a painful ulceration on her back. She was clinically diagnosed as having pyoderma gangrenosum and an appropriate exclusion was performed. She had abnormal results for liver biochemical tests, with a hepatitis-like picture and high titer of antinuclear antibodies. According to the scoring system proposed by the International Autoimmune Hepatitis Group she had `definite' autoimmune hepatitis and responded well to immunesuppressive treatment.

Keyword

Pyoderma gangrenosum; Autoimmune hepatitis

MeSH Terms

Adult
Antibodies, Antinuclear
Arthritis, Rheumatoid
Female
Hepatitis, Autoimmune
Hepatitis, Chronic*
Humans
Inflammatory Bowel Diseases
Liver
Pyoderma Gangrenosum*
Pyoderma*
Ulcer
Antibodies, Antinuclear