Korean J Dermatol.
2003 Nov;41(11):1550-1553.
A Case of Acute Infectious Purpura Fulminans
- Affiliations
-
- 1Department of Dermatology, College of Medicine, Dankook University, Cheonan, Korea. kyccc@dku.edu
- 2Department of Internal Medicine, College of Medicine, Dankook University, Cheonan, Korea.
Abstract
- Purpura fulminans(PF) is a devastating disorder characterized by rapidly progressing hemorrhagic necrosis of the skin, circulatory collapse, and disseminated intravascular coagulation. Histopathologically skin lesions show thrombi within the dermal vessels, a sparse perivascular mononuclear infiltrate, and epidermal necrosis. PF can be classified into three distinct categories: acute infectious PF (sepsis associated PF), hemostasis induced PF, and idiopathic PF. We describe a case of acute infectious PF occurring in 65-year old female with pneumococcal sepsis.