J Korean Pediatr Soc.  1993 May;36(5):725-732.

Three cases of purpura fulminans

Abstract

Purpura fulminans is one of rare consumptive coagulopathy in children. The most common predisposing conditions of purpura fulminans are infectious disease like streptococcal infection and chickenpox. This disease is characterized by ecchymotic lesions that are usually distributed symmetrically on the lower extremities and buttocks. These ecchymotic lesions undergo necrosis, unless there is effective treatment. We experienced 3 cases of purpura fulminans which improved almost completely after early heparin administration. In the case 1, a 12 month old girl, purpura fulminans developed during sepsis and gastroenteritis. In the case 2, a 4 month old boy, purpura fulminans developed during acute sepsis. We reported 3 cases with a brief review of related literature.

Keyword

Purpura fulminans; DIC

MeSH Terms

Buttocks
Chickenpox
Child
Communicable Diseases
Dacarbazine
Female
Gastroenteritis
Heparin
Humans
Infant
Lower Extremity
Male
Necrosis
Purpura Fulminans*
Purpura*
Sepsis
Streptococcal Infections
Dacarbazine
Heparin
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