Korean J Dermatol.
1997 Aug;35(4):693-701.
The Study of the Clinical and Histopatholgical Features of Pilomatricoma
- Affiliations
-
- 1Department of Dermatology, Hallym University, College of Mdeicine, Seoul, Korea.
- 2Department of Pathology, Hallym University, College of Mdeicine, Seoul, Korea.
Abstract
-
BACKGROUND: Pilomatricoma is a rare benign follicular tumor in Orientals.
OBJECTIVE
Clinical and histopathological features of the tumor were analyzed.
METHODS
The medical records and histopathological slides of 19 tumors from 17 patients with pilomatricoma were studied.
RESULTS
The morphology of the tumors were divided into 3 groups :1) elevated, uniform nodules(16 cases), 2) elevated, multilobulated nodules(2 cases), and 3) non-elevated, uniform nodules (1 case). Histologically, the tumors were composed of shadow cells, transitional cells, basaloid cells and squamous cells. Changes of the stroma within the tumors and the stroma overlying the tumors included vascular dilatation, RBC engorgement and infiltration of inflammatory cells. Changes of the epidermis overlying the tumors were found in 14 cases and included hyperkeratosis(14 cases), follicular plugging(2 cases), epidermis invagination(5 cases) and acanthosis nigricans-like change(3 cases).
CONCLUSION
Clinically, pilomatricomas manifested as either a solitary nodule or two nodules. Histologically, several tumors showed palisading of basaloid cells, retraction spaces, lymphoid follicles and acanthosis nigricans-liike epidermal changes in addition to the classic features of pilomatricoma.
