Korean J Gastrointest Endosc.  2001 Sep;23(3):174-178.

A Case of Gastritis Cystica Profunda Associated with Gastric Perforation and Hypertrophic Gastric Folds

Affiliations
  • 1Department of Internal Medicine, Gil Medical Center, Gachon Medical School, Incheon, Korea. dhkang@ghil.com
  • 2Department of Radiology, Gil Medical Center, Gachon Medical School, Incheon, Korea.
  • 3Department of Pathology, Gil Medical Center, Gachon Medical School, Incheon, Korea.

Abstract

Gastritis cystica profunda (GCP) is a rare disease in which cystically dilated gastric foveolae or glands extend into the muscularis mucosae or below. The pathogenesis of GCP has been described as an interruption of the muscularis mucosae and migration of epithelial elements to submucosa caused by presence of suture materials after surgery or erosion of the gastric mucosa in chronic gastritis and ischemia. Macroscopically, GCP may present not only as a giant gastric mucosal folds but also as a submucosal tumor or as solitary or diffuse polyps. An endoscopic ultrasonographic (EUS) findings clearly differ from findings in the other disordes. The combination of EUS and mucosectomy appears to be very useful for the diagnosis of GCP. Therefore, all unnecessary surgical procedures should be avoided in cases of GCP. We report a case of GCP associated with gastric perforation which presented as diffuse giant gastric folds and clinically advanced gastric cancer was suspected.

Keyword

Gastritis cystica profunda (GCP); Perforation; Endoscopic ultrasonography; Mucosectomy

MeSH Terms

Diagnosis
Endosonography
Gastric Mucosa
Gastritis*
Ischemia
Mucous Membrane
Polyps
Rare Diseases
Stomach Neoplasms
Sutures
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