Korean J Gynecol Oncol.  2006 Sep;17(3):213-217.

Comparison of prognosis of FIGO stage IB 1 adenocarcinoma and squamous cell carcinoma who were treated primarily by surgery

• Lim JY
• Song MS
• Hong JS
• Seong SJ
• Kim TJ
• Lim KT
• Shim JU
• Park CT
• Lee KH

Abstract

OBJECTIVE
The objective of this study was to compare clinical and pathologic variables and prognosis of FIGO stage IB 1 adenocarcinoma and squamous cell carcinoma of uterine cervix who were treated primarily by surgery.
METHODS
From May 1982 to October 2000, 2,209 patients with invasive cancer of the uterine cervix were diagnosed and treated at Cheil Hospital. A retrospective review was performed of 533 patients with stage IB1 squamous cell carcinoma (group A) and 84 with adenocarcinoma (group B) of cervix who treated primarily by type 3 hysterectomy and pelvic and paraaortic lymphadenectomy.
RESULTS
Age, endometrial extension, lymph node metastasis and postoperative adjuvant therapy were not different between two group. There were more the lymphovascular space invasion in group A (136 patients, 25.5%) than group B (9 patients, 10.7%) (p<0.0046). 5 year survival were 95.0% vs 93.8% for group A and group B (p=0.75). Using univariate analysis, pelvic node metastasis, paraaortic metastasis, postoperative adjuvant therapy were significant for survival. Multivariate analysis of 5 year survival revealed independent prognostic factor as postoperative adjuvant therapy.
CONCLUSION
Prognosis of FIGO stage IB1 cervical cancer patients who were treated by primarily by type 3 hysterectomy and pelvic and paraaortic lymphadenectomy between adenocarcinoma and squamous cell carcinoma was found to be same.

Keyword

Cervix cancer; Prognosis; Survival rate; Adenocarcinoma

MeSH Terms

Adenocarcinoma*
Carcinoma, Squamous Cell*
Cervix Uteri
Female
Humans
Hysterectomy
Lymph Node Excision
Lymph Nodes
Multivariate Analysis
Neoplasm Metastasis
Prognosis*
Retrospective Studies
Survival Rate
Uterine Cervical Neoplasms