Korean J Hepatobiliary Pancreat Surg.  2001 Jul;5(1):155-162.

Analysis of Risk Factor for Major Complications after Pancreatoduodenectomy

Affiliations
  • 1Department of General Surgery, National Medical Center, Seoul, Korea.

Abstract

BACKGROUND/AIMS: The mortality after pancretoduodenenctomy is decreased to less than 5 % in centers with experience. The morbidity, however, still remains high although the decrease has also been demonstrated. The aim of this study was to identify risk factors responsible for major complications following pancreatoduodenectomy.
METHODS
Various features of forty nine consecutive patients who underwent pancreatoduodenectomy from 1990 to 1999 were statistically analyzed to determine risk factors for major postoperative complications. Anastomotic leakages, intraabdominal hemorrhage and intraabdominal abcess were categorized as major postoperative complication.
RESULTS
In our series, postoperative mortality and morbidy rate were 6.1% and 51.0%, respectively. Seventeen major complications were found in 14 patients(28.6%): 7 cases with pancreaticojejuostomy leakage, 4 cases with biliojejunostomy leakage, 3 cases with intraabdominal hemorrhage and 1 case with intraabdominal abcess. The statistical analysis revealed that episode of intraoperative hypotension was the only independent risk factor for major postoperative complication.(Odds ratio: 25.4849, p=0.0048)
CONCLUSION
Careful intraoperative management for maintenance of adequate blood pressure in hemodynamically unstable patients is important to reduce major complications after pancreatoduodenectomy.

Keyword

Pancreatoduodenectomy; Major complication; Risk factors

MeSH Terms

Anastomotic Leak
Blood Pressure
Hemorrhage
Humans
Hypotension
Mortality
Pancreaticoduodenectomy*
Postoperative Complications
Risk Factors*
Full Text Links
  • KJHBPS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr