Korean J Med.
2009 Apr;76(Suppl 1):S59-S63.
A case of acute myocardial infarction associated with coronary vasospasm in a patient with systemic sclerosis
- Affiliations
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- 1Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea. jjhoon69@yahoo.co.kr
Abstract
- Systemic sclerosis is a chronic, systemic disease that targets the skin, lungs, heart, gastrointestinal tract, kidneys, and musculoskeletal system. Prominent features are vascular damage, immune activation, and the deposition of extravascular matrix. Scleroderma heart disease manifests as myocardial fibrosis. Intermittent spasm of the blood vessels in patients with systemic sclerosis may result in contraction band necrosis, similar to the changes observed in myocardial infarction in patients with atherosclerotic coronary artery disease. Coronary vasospasm has been demonstrated during attacks of cold-induced Raynaud's disease. However, acute myocardial infarction associated with coronary vasospasm in patients with systemic sclerosis has not been reported. We describe a rare case of acute myocardial infarction due to coronary vasospasm associated with systemic sclerosis in a 43-year-old woman who presented with severe chest pain.
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