Korean J Nephrol.
2007 Jul;26(4):508-512.
A Case of Endobronchial Aspergillosis in a Renal Transplant Patient
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Hallym University, Seoul, Korea. jieunmd@hallym.or.kr
- 2Department of General Surgery, College of Medicine, Hallym University, Seoul, Korea.
- 3Department of Pathology, College of Medicine, Hallym University, Seoul, Korea.
- 4Hallym University Kidney Research Institute, Seoul, Korea.
Abstract
- In immunocompromised renal transplant patients, aspergillosis can be a life-threatening opportunistic infection. Aspergillus is a ubiquitous organism in our environment, so pulmonary aspergillosis usually results from the ingrowths of the colonized Aspergillus in bronchial trees, pulmonary cysts or cavities. We have experienced a case of endobronchial aspergillosis developed in a renal transplant patient with neutropenia. Bronchoscopic biopsy revealed a necrotizing Aspergillus bronchitis in the orifice of the lateral segmental bronchus of left upper lobe. The patient received total 2,760 mg intravenous liposomal amphotericin B. There was no endobronchial lesion on follow up bronchoscopy and biopsy was also negative. This case serves as a reminder to clinicians that Aspergillus should be kept in mind as a possible infectious organism in renal transplant patients.
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