Korean J Nephrol.  2006 May;25(3):507-514.

A Case of Dual Malignancy in a Renal Transplanted Recipient

• Lee SY
• Bin HG
• Kim JA
• Lee SJ
• Chang YK
• Lee HK
• Kim SY
• Chang YS
• Bang BK

Abstract

Kidney transplantation is a ideal renal replacement therapy in the patient with end stage renal disease. It made improvement of the patients' life quality but made increase of the incidence of chances of malignant diseases of them. We report a 44-year-old male kidney recipient recently diagnosed as early gastric cancer, had diagnosed previously as malignant lymphoma 6 years ago. He received a kidney from his mother 13 years ago, and then 7 years later he was diagnosed as malignant lymphoma presented as 2.5 cm-sized solitary lung mass. Histologically, it was confirmed as diffuse large cell type lymphoma. After 2-year scheduled chemotherapy and radiation therapy, he achieved complete remission. He was diagnosed as early gastric cancer by routine Upper Gastro-Intestinal Series study. Histologically, it was defined as moderately differentiated adenocarcinoma. He underwent a subtotal gastrectomy (Billoth-II). After the operation, he preserved good graft function with no recurrence of malignancy until now. Briefing our case, a kidney recipient has been serially diagnosed different two kinds of malignancy, malignant lymphoma and early gastric cancer with interval of 7 years. He showed good responses to therapy of malignancies and excellent prognosis. We recommend specific schedule of regular malignancy screening test for kidney recipients with long duration of post-transplantation.

Keyword

Kidney transplant recipient; Malignant lymphoma; Stomach cancer; Dual malignancies

MeSH Terms

Adenocarcinoma
Adult
Appointments and Schedules
Drug Therapy
Gastrectomy
Humans
Incidence
Kidney
Kidney Failure, Chronic
Kidney Transplantation
Lung
Lymphoma
Male
Mass Screening
Mothers
Prognosis
Quality of Life
Recurrence
Renal Replacement Therapy
Stomach Neoplasms
Transplants