J Korean Soc Radiol.  2015 Nov;73(5):343-346. 10.3348/jksr.2015.73.5.343.

Cystic Papillary Renal Cell Carcinoma Arising from an Involutional Multicystic Dysplastic Kidney

• Kim JJ
• Kim BS
• Huh JS
• Park KG
• Choi GM
• Kim SH
• Maeng YH

• KMID: 2079571
• DOI: http://doi.org/10.3348/jksr.2015.73.5.343

Abstract

Multicystic dysplastic kidney is a common cystic renal disease that often occurs in infancy. Recent studies demonstrate the possibility for spontaneous involution of a dysplastic kidney. In such cases, the prognosis is generally excellent and there is a very low incidence of complications. Complications associated with multicystic dysplastic kidney include pain, infection, hypertension, and neoplasia. Renal cell carcinomas are extremely rare in multicystic dysplastic kidneys. To our knowledge, no case report has described a radiologic finding of renal cell carcinoma arising from an involutional multicystic dysplastic kidney. We report a case of histopathologically validated cystic papillary renal cell carcinoma arising from an involutional multicystic dysplastic kidney and describe its sonographic and CT features.

MeSH Terms

Carcinoma, Renal Cell*
Hypertension
Incidence
Kidney
Kidney Diseases, Cystic
Multicystic Dysplastic Kidney*
Prognosis
Ultrasonography

Figure

• 

  Fig. 1 33-year-old man with a left retroperitoneal mass. A. Ultrasonogram of the left intercostal space shows a cystic mass with multiple, discrete nodularites (arrows) in the left renal fossa. However, the left kidney was not clearly visible. B. Unenhanced CT image shows a cystic mass with a linear calcification. C-E. Contrast-enhanced CT images obtained during the nephrographic phase show several focal nodular enhancements (long arrows) in the cyst wall. Note the triangular, regressed, multicystic dysplastic kidney (short arrows) between the adrenal gland and the cystic mass. The normal parenchyma of the left kidney is not visible.

• 

  Fig. 2 Histopathologic findings of a surgically resected, left retroperitoneal mass. A. The cut surface of the surgical specimen shows tan papillary tumor tissue on the inner surface of the wall. B. Photomicrograph showing immature, tubule-like structures scattered in the fibrous cystic wall (arrows), which is a dysplastic kidney (hematoxylin and eosin stain, × 100). C. Photomicrograph showing low-grade renal cell carcinoma with papillary arrangement (arrows) (hematoxylin and eosin stain, × 40).

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