Korean J Nephrol.
2003 Jan;22(1):148-155.
H+ -ATPase Pump Defects of Distal Renal Tubular Acidosis as Initial Manifestation of Systemic Lupus Erythematosus
- Affiliations
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- 1Department of Internal Medicine, School of Medicine, Ajou University, Suwon, Korea. nephrohs@ajou.ac.kr
- 2Department of Pathology, School of Medicine, Ajou University, Suwon, Korea.
- 3Department of Anatomy, The Catholic University of Korea, Medical College, Seoul, Korea.
Abstract
- Systemic lupus erythematosus (SLE) is a multisystem disease with marked variability in its manifestation. Tubulointerstitial involvement is well recognized in SLE. But usually the tubular dysfunction is latent and usually presents after diagnosis of SLE. We report a 20 years old female whose initial symptom of SLE was distal renal tubular acidosis (RTA). She presented with severe muscle weakness at emergency room with laboratory fingding consistent with distal RTA. After several months she developed fever, arthritis, serologic fingding which was compatible to diagnose SLE. We report a case whose initial symptom of SLE had been distal RTA.
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