Korean J Nephrol.  2001 Jul;20(4):714-718.

Exercise-induced Acute Renal Failure in a Patient with Renal Hypouricemia

• Chang HH
• Kim HJ
• Lee JJ
• Kim JH
• Lee TW
• Ihm CG
• Kim MJ

Abstract

We report a case of exercise-induced acute renal failure associated with renal hypouricemia in a 35- year-old man who complained of oliguria and back pain after swimming. Laboratory tests revealed that serum blood urea nitrogen and creatinine level were elevated, the serum uric acid concentration was subnormal(2.1 mg/dL). After conservative treatment, renal function was recovered. But, uric acid level decreased to 0.4 mg/dL. In addition, there was no supression of urate clearance to creatinine clearnace ratio(CUA/CCr) following the administration of pyrazinamide, and no increase of CUA/CCr after benzbromarone. Therefore, we think the cause of renal hypouricemia in this patient may be the subtotal defect in the urate transport.

Keyword

Renal hypouricemia; Acute renal failure; Exercise; Urate transport

MeSH Terms

Acute Kidney Injury*
Back Pain
Benzbromarone
Blood Urea Nitrogen
Creatinine
Humans
Oliguria
Pyrazinamide
Swimming
Uric Acid
Benzbromarone
Creatinine
Pyrazinamide
Uric Acid