Korean J Obstet Gynecol.  2012 Feb;55(2):119-122. 10.5468/KJOG.2012.55.2.119.

Pregnancy in woman with Klippel-Trenaunay syndrome: A case report

• Jeon GH
• Kim YM
• Chun S
• Cho HJ
• Ji YI
• Jeong CH

• KMID: 2078125
• DOI: http://doi.org/10.5468/KJOG.2012.55.2.119

Abstract

The Klippel-Trenaunay syndrome is rare congenital disease characterized by a triad of cutaneous vascular malformations, varicose veins, and hypertrophy of bone and soft tissue. Although several cases of pregnancy in women with Klippel-Trenaunay syndrome were reported as there may be increased risk of pregnancy- and/or delivery-associated complications such as varicosities, thromboembolism and hemorrhage, there is little general information regarding how to deal with pregnancy in patients with Klippel-Trenaunay syndrome and their obstetric outcome. We describe the case of a woman suffering from Klippel-Trenaunay syndrome delivering a healthy child with a brief review of concerned literature.

Keyword

Klippel-Trenaunay syndrome; Pregnancy; Complications

MeSH Terms

Child
Female
Hemorrhage
Humans
Hypertrophy
Klippel-Trenaunay-Weber Syndrome
Pregnancy
Stress, Psychological
Thromboembolism
Varicose Veins
Vascular Malformations

Figure

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  Fig. 1 The swollen and slightly enlarged right leg was seen at 7 weeks of pregnancy age. Cutaneous capillary hemangiomas and varicose veins were extended on the medial and dorsal side of the right leg.

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  Fig. 2 Transvaginal sonography reveals a 27 × 15 mm sized subchorionic hemorrhage during 1st trimester of pregnancy without definite hemangiomas around uterus.

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  Fig. 3 Fibrin thrombi in fetal chorionic vessels were found in the placental biopsy (H&E, ×100).

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