Korean J Obstet Gynecol.  2007 Oct;50(10):1308-1312.

Maternal-neonatal outcome in HELLP syndrome and severe preeclampsia

• Jin KH
• Kim MJ
• Ahn HY
• Kil KC
• Park IY
• Lee Y
• Lee GS
• Shin JC
• Kim SJ

Abstract

OBJECTIVE
To assess the clinical characteristics, laboratory findings, the maternal and neonatal complications between HELLP syndrome and severe preeclampsia.
METHODS
We reviewed the material and neonatal charts of 34 pregnancies complicated by HELLP syndrome and 40 pregnancies complicated by severe preeclampsia managed at our hospital between January, 2001 and December, 2005. We compared the clinical characteristics, laboratory findings, the maternal and neonatal complications between two groups. Results were compared by student T test, chi-square test.
RESULTS
Our study showed that in HELLP syndrome patients had the less gestational age at admission, gestational age at delivery, the lower platelet counts, the higher AST, ALT, LDH, and the longer hospitalization period than in severe preeclampsia. Steroid (dexamethasone) use, cesarean delivery rate and MgSO4 use were more frequent in HELLP syndrome than severe preeclampsia. Neonatal birth weight was lower with HELLP syndrome. There was no significant difference in maternal and neonatal complications.
CONCLUSION
HELLP syndrome need to be recognized a unique form of severe preeclampsia. It was associated with serious maternal and fetal mortality, the appropriate management would be done by early diagnosis using laboratory tests.

Keyword

HELLP syndrome; Severe preeclampsia

MeSH Terms

Birth Weight
Early Diagnosis
Female
Fetal Mortality
Gestational Age
HELLP Syndrome*
Hospitalization
Humans
Platelet Count
Pre-Eclampsia*
Pregnancy