Korean J Obstet Gynecol.
2007 Oct;50(10):1299-1307.
Contemporary clinical trials in uterine corpus malignancies
- Affiliations
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- 1Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Korea. hsryu@ajou.ac.kr
Abstract
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Uterine cancer is the most common gynecologic malignancy in Western countries. In Korea, its incidence has been rising, and the increased incidence is associated with a rising death rate. The first two decades of endometrial cancer study by the GOG began with a prospective, surgicopathologic staging trial that was the cornerstone for development of all subsequent trials. The therapeutic strategies were tailored to disease extent - low risk, intermediate risk, and high risk groups of patients. There were great advances in the area of chemotherapeutic agents through a number of extensive phase II trials. New trials of these agents have been opened for the patients with advanced or recurrent uterine cancers.