Korean J Obstet Gynecol.  2002 Nov;45(11):1946-1950.

Genetic amniocentesis after multifetal pregnancy reduction

Affiliations
  • 1Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University, seoul, Korea.

Abstract


OBJECTIVE
This study is directed to evaluate the pregnancy loss rate resulting from genetic amniocentesis after multifetal pregnancy reduction.
METHODS
From March 1998 to April 1999, total 145 patients with multifetal pregnancy were included in this study. Pregnancy loss in a study population of 44 patients who underwent genetic amniocentesis after multifetal pregnancy reduction were compared with a control group of 99 patients who did not have genetic amniocentesis after multifetal pregnancy reduction.
RESULTS
The pregnancy loss rate in patients who underwent genetic amniocentesis after multifetal pregnancy reduction was 2.2% (1/44) compared with 4% (4/99) in the controls (P>.05). In the study group, one woman lost her pregnancy at 19 weeks' gestation, 3 weeks after the genetic amniocentesis, and the predisposing factor was spontaneous rupture of membranes.
CONCLUSION
Genetic amniocentesis following multifetal pregnancy reduction does not increase the risk of pregnancy loss.

Keyword

Multifetal pregnancy reduction; Amniocentesis; Pregnancy loss

MeSH Terms

Amniocentesis*
Causality
Female
Humans
Membranes
Pregnancy
Pregnancy Reduction, Multifetal*
Rupture, Spontaneous
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