Korean J Obstet Gynecol.  2002 Sep;45(9):1633-1635.

A Case of Spontaneous Pneumothorax During Chemotherapy for Metastatic Choriocarcinoma

Affiliations
  • 1Department of Obstetrics and Gynecology, Korea Cancer Center Hospital, Seoul, Korea.

Abstract

Spontaneous pneumothorax is a rare complication of pulmonary metastatic disease, most often following chemotherapy for osteogenic sarcomas, primary lung cancer or malignant germ cell tumors. Intensive chemotherapy may theoretically increase the risk of pneumothorax in patients with manifest or occult lung metastases by inducing rapid lysis of the tumor tissue and by interfering with repair processes. We present a case of patient with spontaneous pneumothorax after the introduction of chemotherapy for metastatic choriocarcinoma and review the literature and discuss the possible pathophysiologic mechanisms.

Keyword

chemotherapy; lung metastases; spontaneous pneumothorax

MeSH Terms

Choriocarcinoma*
Drug Therapy*
Female
Humans
Lung
Lung Neoplasms
Neoplasm Metastasis
Neoplasms, Germ Cell and Embryonal
Osteosarcoma
Pneumothorax*
Pregnancy
Full Text Links
  • KJOG
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr