Korean J Obstet Gynecol.
2002 Sep;45(9):1633-1635.
A Case of Spontaneous Pneumothorax During Chemotherapy for Metastatic Choriocarcinoma
- Affiliations
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- 1Department of Obstetrics and Gynecology, Korea Cancer Center Hospital, Seoul, Korea.
Abstract
- Spontaneous pneumothorax is a rare complication of pulmonary metastatic disease, most often following chemotherapy for osteogenic sarcomas, primary lung cancer or malignant germ cell tumors. Intensive chemotherapy may theoretically increase the risk of pneumothorax in patients with manifest or occult lung metastases by inducing rapid lysis of the tumor tissue and by interfering with repair processes. We present a case of patient with spontaneous pneumothorax after the introduction of chemotherapy for metastatic choriocarcinoma and review the literature and discuss the possible pathophysiologic mechanisms.
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