Korean J Obstet Gynecol.  2002 Sep;45(9):1485-1490.

Frequency of fetal anomaly and perinatal outcome in polyhydramnios

• Pak K
• Kim SJ
• Lim HJ
• Kim EJ
• Lee WS
• Oh MJ
• Choi JS
• Kuol H
• Jung SH
• Ahn HK
• Han JY
• Kim MY
• Ryu HM
• Choi KH
• Yang JH

Abstract

OBJECTIVE
To determine the frequency of fetal anomaly and perinatal outcome in pregnant women with polyhydramnios.
METHODS
Ultrasound examinations from January 1998 to August 2001 were reviewed to identify 170 patients with singleton pregnancy which diagnosed polyhydramnios. Frequency of fetal anomaly and perinatal outcomes were compared with amniotic fluid index (AFI) 20.0-25.0 cm as group 1 and AFI >25.0 cm as group 2.
RESULTS
The prevalence of polyhydramnios was 0.54% (170/31,358). The types of structural anomalies were gastrointestinal system (10/34, 29.4%), genitourinary system (9/34, 26.5%), central nervous system (CNS, 6/34, 17.7%), cardiovascular system (CVS, 3/34, 8.8%), neuromuscular system (2/34, 5.9%), respiratory system (1/34, 2.9%) and others (3/34, 8.8%). The structural anomaies between two groups were significantly different. The rate of cesarean section, low 5-min Apgar score (<7), large for gestational age (LGL, 95 percentile), Nursery Intensive Care Unit (NICU) visitation and perinatal death were not significantly different between two groups.
CONCLUSION
The prevalence of fetal anomaly was 20% (34/170) and significantly different between two groups (p=0.0143). However, the perinatal outcome was not significantly different between two groups. CNS, gastrointestinal system and CVS anomalies were more frequent in group 2 (AFI>25.0 cm) and genitourinary system anomaly was dominant in group 1 (AFI 20.0-25.0 cm). Polyhydramnios (AFI>25.0 cm) indicated an increased risk of severe fetal anomaly.

Keyword

Polyhydramnios; Fetal anomaly; Perinatal outcome

MeSH Terms

Amniotic Fluid
Apgar Score
Cardiovascular System
Central Nervous System
Cesarean Section
Female
Gestational Age
Humans
Intensive Care Units
Nurseries
Polyhydramnios*
Pregnancy
Pregnant Women
Prevalence
Respiratory System
Ultrasonography
Urogenital System