Korean J Obstet Gynecol.  1997 Oct;40(10):2241-2245.

The Significance of Cervical Erosion with Benign Cellular Change on Papanicolaou Smear

• Joeng MJ
• Park KJ
• Yoo KY

Abstract

The significance of cervical erosion with benign cellular change on Papanicolaou smear has not been evaluated. A retrospective review of 430 coloscopically directed punch biopsies performed over 15 months revealed 206 cases who had a benign cellular change on cytologic smear. Of these 206 smears, 48(23%) had clear cervix without erosion, 99(48%) had mild erosion on cervix, 41(20%) had moderate cervical erosion and 18(9%) had severe cervical erosion. The false negative rate that revealed more than mild dysplasia on histologic diagnosis was 2% in patients without cervical erosion, 3% in patients with mild cervical erosion, 5 % in patients with moderate cervical erosion, and 11% in patients with severe cervical er- osion. Koilocytotic change that suggested human papilloma virus infection was 17% in each group regardless cervical erosion. In conclusion, benign cellular change on Pap smears in patients with severe cervical erosion may be associated with significant cervical cancer pathology.

Keyword

Papanicolaou smear; Benign cellular change; Cervical erosion

MeSH Terms

Biopsy
Cervix Uteri
Diagnosis
Female
Humans
Papanicolaou Test*
Papilloma
Pathology
Retrospective Studies
Uterine Cervical Neoplasms