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Application time and persistence of transcranial direct current stimulation (tDCS) against neuronal death resulting from transient cerebral ischemia

Lee JH, Jung BH, Yoo KY

Background: Transcranial direct current stimulation (tDCS) has been studied as a tool to stimulate the functional recovery of neurons after stroke. Although this device has recently begun to be utilized...
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Controlled releasing properties of gelatin nanofabric device containing chlorhexidine

Park DU, Um HS, Chang BS, Lee SY, Yoo KY, Choi WY, Lee JK

We aimed to evaluate the degradation and antimicrobial activity of novel chlorhexidine-containing gelatin nanofabric devices and their cytotoxicity in animals. The electro-spun device with a size of 3×4×0.4 mm 3...
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Flavonoids as anti-inflammatory and neuroprotective agents

Lee H, Selvaraj B, Yoo KY, Ko SH

Neuroinflammation is known as the main mechanism implicated in the advancement of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. The main feature of neuroinflammation is associated with the...
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Fluid management in perioperative and critically ill patients

Kang D, Yoo KY

Fluid therapy to restore and/or maintain tissue perfusion may affect patient outcomes in perioperative, emergency, and intensive care. Kinetic analyses and outcome-oriented studies have provided more insight into fluid management....
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Molecular Genetics of von Willebrand Disease in Korean Patients: Novel Variants and Limited Diagnostic Utility of Multiplex Ligation-Dependent Probe Amplification Analyses

Kim HJ, Kim SK, Yoo KY, Lee KO, Yun JW, Kim SH, Kim HJ, Park SK

BACKGROUND: von Willebrand disease (VWD), characterized by quantitative or qualitative defects of von Willebrand factor (VWF), is the most common inheritable bleeding disorder. Data regarding the genetic background of VWD...
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Association between Body Mass Index and Gastric Cancer Risk According to Effect Modification by Helicobacter pylori Infection

Jang J, Cho EJ, Hwang Y, Weiderpass E, Ahn C, Choi J, Chang SH, Shin HR, Lim MK, Yoo KY, Park SK

PURPOSE: Few studies investigated roles of body mass index (BMI) on gastric cancer (GC) risk according to Helicobacter pylori infection status. This study was conducted to evaluate associations between BMI...
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Study on the Changes in Distributions and Expressions of Aquaporin5 (AQP5) in Salivary Glands of Mice After Alcohol Ingestion

Lim YS, Yoo KY

Alcohol intake is known to affect various organs in the human body, causing reduction of salivation in the oral cavity. Hypo-salivation effect of alcohol is a common feature, but the...
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Determination of the optimal diabetes duration for bone regeneration experiments in an alloxan-induced diabetic rabbit calvarial defect model

Jeong SH, Jung BH, Yoo KY, Um HS, Chang BS, Lee JK, Choi WY

PURPOSE: The purpose of this study was to evaluate the optimal diabetes duration for bone regeneration experiments in an alloxan monohydrate (ALX)–induced diabetic rabbit calvarial defect model by evaluating the...
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Clinical and Radiological Evaluation After Chemical Synovectomy With Rifampicin in Hemophilic Arthropathy: Korean Experience With a 2-Week Interval Protocol

Suh HC, Kim DK, Kang SH, Seo KM, Kim HS, Lee JY, Lee SY, Yoo KY

OBJECTIVE: To assess the clinical outcome of chemical synovectomy with rifampicin in hemophilic arthropathy by using the World Federation of Hemophilia (WFH) scoring system and plain radiograph. METHODS: We performed rifampicin...
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The 2nd Meeting of National Control Laboratories for Vaccines and Biologicals in the Western Pacific

Oh H, Shin J, Lee CK, Ochiai M, Nojima K, Lim CK, Raut S, Lisovsky I, Williams S, Yoo KY, Shin DY, Ato M, Ye Q, Han K, Lee C, Lee N, Hong JY, Jung K, Van Hung P, Jeong J

The Second Meeting of the National Control Laboratories for Vaccines and Biologicals in the Western Pacific, was jointly organized by the National Institute of Food and Drug Safety Evaluation of...
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Educational Interventions to Enhance Adherence to Prophylactic Treatment in Korean Hemophilia Patients

Na JH, Yoo KY, Kim JY, Park SK, Kim SK, Choi EJ

BACKGROUND: A patient's adherence to prophylactic treatment is one of the most significant factors to achieve desired outcomes, in regards to the quality of life and treatment cost-effectiveness. The aim...
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Effectiveness of Gastric Cancer Screening on Gastric Cancer Incidence and Mortality in a Community-Based Prospective Cohort

Kim H, Hwang Y, Sung H, Jang J, Ahn C, Kim SG, Yoo KY, Park SK

PURPOSE: This study was performed to investigate the effectiveness of gastric cancer (GC) screening methods in a community-based prospective cohort of the Korean Multi-center Cancer Cohort (KMCC) with over a...
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Global hemostatic assay of different target procoagulant activities of factor VIII and factor IX

Yoo KY, Jung SY, Hwang SH, Lee SM, Park JH, Nam HJ

BACKGROUND: Korean National Health Insurance reimburses factor VIII (FVIII) and factor IX (FIX) clotting factor concentrate (CFC) infusions to discrepant activity levels, allowing elevation of FVIII activity to 60 IU/dL...
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Safety and Efficacy of B-domain Deleted Third Generation Recombinant Factor VIII (GreenGene Fâ„¢) in Korean Patients with Hemophilia A: Data from a Post-marketing Surveillance Study

Kim SK, Yoo KY, Lee KS, Hwang T, Choi YM, Choi EJ, Park SK

BACKGROUND: New B-domain deleted third generation recombinant factor VIII (FVIII; GreenGene Fâ„¢, beroctocog alfa) was launched in 2010. We determined safety and efficacy of GreenGene Fâ„¢ during routine clinical practice...
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Risk Reduction of Breast Cancer by Childbirth, Breastfeeding, and Their Interaction in Korean Women: Heterogeneous Effects Across Menopausal Status, Hormone Receptor Status, and Pathological Subtypes

Jeong SH, An Y, Choi JY, Park B, Kang D, Lee MH, Han W, Noh DY, Yoo KY, Park SK

OBJECTIVES: The purpose of this study was to examine the associations of childbirth, breastfeeding, and their interaction with breast cancer (BC) risk reduction, and to evaluate the heterogeneity in the...
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A Multicenter Study on Korean von Willebrand Disease Realities

Seol JH, Kim HJ, Kim SK, Yoo KY, Shim YJ, Baek HJ, Park YS, Choi EJ, Park SK

BACKGROUND: von Willebrand disease (VWD) is the most common inherited bleeding disorder with a prevalence of up to 1%. However in Korea, only 126 VWD patients were registered in Korea...
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Determination of the critical diabetes duration in a streptozotocin-induced diabetic rat calvarial defect model for experimentation regarding bone regeneration

Kim HJ, Jung BH, Yoo KY, Han JW, Um HS, Chang BS, Lee JK

PURPOSE: The purpose of this study was to determine the critical diabetes duration in a streptozotocin (STZ)-induced diabetic rat calvarial defect model for experimentation regarding bone regeneration by evaluating the...
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Study on Changes in Endogenous Stem Cells in the Salivary Gland of Streptozotocin-induced Diabetic Rats

Jung BH, Lee HS, Yoo KY

Type1 diabetes mellitus (DM) is generally known to be caused by destruction of insulin-producing pancreatic β cells or an immune-related problem. Polydipsia is a representative symptom of DM, and it...
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Direct Acting Antiviral Agents in Korean Patients with Chronic Hepatitis C and Hemophilia Who Are Treatment-Naïve or Treatment-Experienced

Lee HW, Yoo KY, Won JW, Kim HJ

BACKGROUND/AIMS: Chronic hepatitis C (CHC) is a major comorbidity in patients with hemophilia. METHODS: Patients (n=30) were enrolled between September 2015 and April 2016. Twenty-six patients were genotype 1 (1b, n=21;...
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Role of vasopressin in current anesthetic practice

Park KS, Yoo KY

Arginine vasopressin (AVP), also known as antidiuretic hormone, is a peptide endogenously secreted by the posterior pituitary in response to hyperosmolar plasma or systemic hypoperfusion states. When administered intravenously, it...
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