Korean J Obstet Gynecol.  1997 Oct;40(10):2130-2136.

A Study of Clinical Parameters Influencing Human Zona Pellucida Thickness

• Park HJ
• Han HD
• Hong M
• Han SW
• Chung IB
• Lee YJ

Abstract

The purpose of present study was to assess which parameters influence human oocyte zona pellucida(ZP). Zone pellucida thickness was evaluated in 124 oocytes of 16 cycles IVF-ET with intracytoplasmic sperm injection(ICSI) between July 1995 and October 1995 at the department of obstetrics and Gynecology, Yonsei university, Wonju Christian Hospital. The zone pullucida thickness was 17.7+/-2.0micronm(mean+/-SD) for 107 metaphase II oocy- tes. The zona pullucida thickness was singinficantly different according to maximum estr- adiol(E2) value ; The mean thickness of Zona pellucida was thinner below 2000 pg/ml of E2 value than that above 2001 pg/ml of E2 value(p<0.05). And when the metaphase II oocytes was cultured for 3 days, the mean thickness of Zona pellucida was thinner than that of metaphase II oocytes whether fertilization or not(p<0.01, p<0.03). But the Zona pellucida thickness was not significantly different from the age of women and the oocyte maturation status(p>0.05).

Keyword

Zona pellucida thickness; Intracytoplasmic sperm injection; In vitro fertilization and embryo transfer

MeSH Terms

Female
Fertilization
Gangwon-do
Gynecology
Herpes Zoster*
Humans*
Metaphase
Obstetrics
Oocytes
Sperm Injections, Intracytoplasmic
Spermatozoa
Zona Pellucida*