Korean J Obstet Gynecol.
1998 Feb;41(2):636-641.
A Novel, Balanced Translocation t ( 7 ; 10 ) ( q22 ; q26 ) in a Couple with Repeated Spontaneous Abortion
Abstract
-
Chromosomal abnormality is one of the main causes for the repeated spontaneous abortion. A 31-year-old patient, otherwise normal woman who had experienced three consecutive miscarriage were karyotyped using peripheral blood cells. The patient has been found to have a novel, balanced translocation, with a formal karyotype of 46,XX,der (7)t (7;10) (q22;q26). The present result suggests that chromosomal analysis may be necessary for diagnosing the couples experiencing repeated spontaneous abortion.