Korean J Pediatr.  2007 May;50(5):469-475. 10.3345/kjp.2007.50.5.469.

Closure of secundum atrial septal defect: comparison between percutaneous and surgical occlusion

• Kim NY
• Kwon HJ
• Choi DY
• Jung MJ
• Choi CH
• Kim SH

• KMID: 2072884
• DOI: http://doi.org/10.3345/kjp.2007.50.5.469

Abstract

PURPOSE: This study was performed to compare the safety, efficacy and clinical results of the Amplatzer septal occluder (ASO) for closure of secundum atrial septal defect (ASD) with surgery.
METHODS
One hundred fifteen patients diagnosed as isolated secundum ASD in Gil Medical Center, Gachon University of Medicine from January 2000 to July 2006 were included. Seventy patients underwent surgical repair of ostium secundum ASD. Forty-five consecutive patients were treated with percutaneous closure using ASO. We compared the mortality, morbidity, hospital stay, and efficacy between two groups.
RESULTS
Male to female ratio was 1:2.4. The mean age and the size of defects were not statistically different. No mortality occurred in either group. The success rate was 97.8% in the device group and 100% in the surgical group. The overall rate of complications was higher in the surgical group than in the device group (64.0 vs. 15.6%, P<0.05). Hospital stay was shorter in the device group than in the surgical group (4.2+/-1.2 vs. 12.4+/-4.7 days, P<0.0001). Residual shunt rates were more frequent in the device group (8.9%) than in the surgical group (4.3%) at discharge. All residual shunts disappeared at 3 months follow-up.
CONCLUSION
Percutaneous closure of ASD using ASO is a safe and effective alternative to surgical repair. The indications of percutaneous ASD closure with ASO would be expanded by accumulation of experiences and evolutions of device.

Keyword

Atrial septal defect; Percutaneous; Surgery

MeSH Terms

Female
Follow-Up Studies
Heart Septal Defects, Atrial*
Humans
Length of Stay
Male
Mortality
Septal Occluder Device