Yonsei Med J.  2014 Nov;55(6):1611-1616. 10.3349/ymj.2014.55.6.1611.

Underweight Body Mass Index as a Predictive Factor for Surgical Site Infections after Laparoscopic Appendectomy

Affiliations
  • 1Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. ravic@naver.com

Abstract

PURPOSE
Analyses of risk factors associated with surgical site infections (SSIs) after laparoscopic appendectomy (LA) have been limited. Especially, the association of an underweight body mass index (BMI) with SSIs has not been clearly defined. This study aimed to identify the impact of underweight BMI in predicting SSIs after LA.
MATERIALS AND METHODS
The records of a total of 101 consecutive patients aged > or =16 years who underwent LA by a single surgeon between March 2011 and December 2012 were retrieved from a prospectively collected database. The rate of SSIs was compared among the underweight, normal and overweight and obese groups. Also, univariate and multivariate analyses were performed to identify the factors associated with SSIs.
RESULTS
The overall rate of SSIs was 12.8%. The superficial incisional SSI rate was highest in the underweight group (44.4% in the underweight group, 11.0% in the normal group, and 0% in the overweight and obese group, p=0.006). In univariate analysis, open conversion and being underweight were determined to be risk factors for SSIs. Underweight BMI was also found to be a significant predictor for SSIs in multivariate analysis (odds ratio, 10.0; 95% confidence interval, 2.0-49.5; p=0.005).
CONCLUSION
This study demonstrated underweight BMI as being associated with SSIs after LA. Surgeons should be more cautious to prevent SSIs in patients that are underweight when performing LA.

Keyword

Appendicitis; laparoscopic appendectomy; surgical site infection; body mass index; morbidity

MeSH Terms

Adult
Aged
Appendectomy/*adverse effects
Appendicitis/*surgery
*Body Mass Index
Body Weight
Female
Humans
*Laparoscopy
Male
Middle Aged
Multivariate Analysis
Obesity/complications
Odds Ratio
Prospective Studies
Risk Factors
Surgical Wound Infection/*etiology
Thinness/*complications
Treatment Outcome

Reference

1. Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. Guideline for Prevention of Surgical Site Infection, 1999. Am J Infect Control. 1999; 27:97–132.
Article
2. Emori TG, Gaynes RP. An overview of nosocomial infections, including the role of the microbiology laboratory. Clin Microbiol Rev. 1993; 6:428–442.
Article
3. Urban JA. Cost analysis of surgical site infections. Surg Infect (Larchmt). 2006; 7:Suppl 1. S19–S22.
Article
4. Addiss DG, Shaffer N, Fowler BS, Tauxe RV. The epidemiology of appendicitis and appendectomy in the United States. Am J Epidemiol. 1990; 132:910–925.
Article
5. Saia M, Buja A, Baldovin T, Callegaro G, Sandonà P, Mantoan D, et al. Trend, variability, and outcome of open vs. laparoscopic appendectomy based on a large administrative database. Surg Endosc. 2012; 26:2353–2359.
Article
6. Sauerland S, Jaschinski T, Neugebauer EA. Laparoscopic versus open surgery for suspected appendicitis. Cochrane Database Syst Rev. 2010; CD001546.
Article
7. Wei HB, Huang JL, Zheng ZH, Wei B, Zheng F, Qiu WS, et al. Laparoscopic versus open appendectomy: a prospective randomized comparison. Surg Endosc. 2010; 24:266–269.
Article
8. Tiwari MM, Reynoso JF, Tsang AW, Oleynikov D. Comparison of outcomes of laparoscopic and open appendectomy in management of uncomplicated and complicated appendicitis. Ann Surg. 2011; 254:927–932.
Article
9. Kim CB, Kim MS, Hong JH, Lee HY, Yu SH. Is laparoscopic appendectomy useful for the treatment of acute appendicitis in Korea? A meta-analysis. Yonsei Med J. 2004; 45:7–16.
Article
10. Lee WS, Choi ST, Lee JN, Kim KK, Park YH, Lee WK, et al. Single-port laparoscopic appendectomy versus conventional laparoscopic appendectomy: a prospective randomized controlled study. Ann Surg. 2013; 257:214–218.
Article
11. Teoh AY, Chiu PW, Wong TC, Poon MC, Wong SK, Leong HT, et al. A double-blinded randomized controlled trial of laparoendoscopic single-site access versus conventional 3-port appendectomy. Ann Surg. 2012; 256:909–914.
Article
12. Anaya DA, Dellinger EP. The obese surgical patient: a susceptible host for infection. Surg Infect (Larchmt). 2006; 7:473–480.
Article
13. Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, Flegal KM, Guo SS, Wei R, et al. CDC growth charts: United States. Adv Data. 2000; 1–27.
14. Cole TJ, Bellizzi MC, Flegal KM, Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ. 2000; 320:1240–1243.
Article
15. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control. 2008; 36:309–332.
Article
16. Suh YJ, Jeong SY, Park KJ, Park JG, Kang SB, Kim DW, et al. Comparison of surgical-site infection between open and laparoscopic appendectomy. J Korean Surg Soc. 2012; 82:35–39.
Article
17. Katkhouda N, Mason RJ, Towfigh S, Gevorgyan A, Essani R. Laparoscopic versus open appendectomy: a prospective randomized double-blind study. Ann Surg. 2005; 242:439–448.
Article
18. Kehagias I, Karamanakos SN, Panagiotopoulos S, Panagopoulos K, Kalfarentzos F. Laparoscopic versus open appendectomy: which way to go? World J Gastroenterol. 2008; 14:4909–4914.
Article
19. Pedersen AG, Petersen OB, Wara P, Rønning H, Qvist N, Laurberg S. Randomized clinical trial of laparoscopic versus open appendicectomy. Br J Surg. 2001; 88:200–205.
20. Wilson DG, Bond AK, Ladwa N, Sajid MS, Baig MK, Sains P. Intra-abdominal collections following laparoscopic versus open appendicectomy: an experience of 516 consecutive cases at a district general hospital. Surg Endosc. 2013; 27:2351–2356.
Article
21. Katkhouda N, Friedlander MH, Grant SW, Achanta KK, Essani R, Paik P, et al. Intraabdominal abscess rate after laparoscopic appendectomy. Am J Surg. 2000; 180:456–459.
Article
22. Li JC, Lee JF, Ng SS, Yiu RY, Hon SS, Leung WW, et al. Conversion in laparoscopic-assisted colectomy for right colon cancer: risk factors and clinical outcomes. Int J Colorectal Dis. 2010; 25:983–988.
Article
23. Piskun G, Kozik D, Rajpal S, Shaftan G, Fogler R. Comparison of laparoscopic, open, and converted appendectomy for perforated appendicitis. Surg Endosc. 2001; 15:660–662.
Article
24. Kouwenhoven EA, Repelaer van, van Erp WF. Fear for the intraabdominal abscess after laparoscopic appendectomy: not realistic. Surg Endosc. 2005; 19:923–926.
Article
25. Lujan Mompean JA, Robles Campos R, Parrilla Paricio P, Soria Aledo V, Garcia Ayllon J. Laparoscopic versus open appendicectomy: a prospective assessment. Br J Surg. 1994; 81:133–135.
26. Hirao M, Tsujinaka T, Imamura H, Kurokawa Y, Inoue K, Kimura Y, et al. Overweight is a risk factor for surgical site infection following distal gastrectomy for gastric cancer. Gastric Cancer. 2013; 16:239–244.
Article
27. Smith RL, Bohl JK, McElearney ST, Friel CM, Barclay MM, Sawyer RG, et al. Wound infection after elective colorectal resection. Ann Surg. 2004; 239:599–605.
Article
28. Pessaux P, Msika S, Atalla D, Hay JM, Flamant Y. French Association for Surgical Research. Risk factors for postoperative infectious complications in noncolorectal abdominal surgery: a multivariate analysis based on a prospective multicenter study of 4718 patients. Arch Surg. 2003; 138:314–324.
Article
29. Nishida T, Sakakibara H. Association between underweight and low lymphocyte count as an indicator of malnutrition in Japanese women. J Womens Health (Larchmt). 2010; 19:1377–1383.
Article
30. Kahan BD. Nutrition and host defense mechanisms. Surg Clin North Am. 1981; 61:557–570.
Article
31. Law DK, Dudrick SJ, Abdou NI. Immunocompetence of patients with protein-calorie malnutrition. The effects of nutritional repletion. Ann Intern Med. 1973; 79:545–550.
Article
32. Oh CA, Kim DH, Oh SJ, Choi MG, Noh JH, Sohn TS, et al. Nutritional risk index as a predictor of postoperative wound complications after gastrectomy. World J Gastroenterol. 2012; 18:673–678.
Article
33. Myron Johnson A, Merlini G, Sheldon J, Ichihara K. Scientific Division Committee on Plasma Proteins (C-PP), International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). Clinical indications for plasma protein assays: transthyretin (prealbumin) in inflammation and malnutrition. Clin Chem Lab Med. 2007; 45:419–426.
34. Ruiz-López MD, Artacho R, Oliva P, Moreno-Torres R, Bolaños J, de Teresa C, et al. Nutritional risk in institutionalized older women determined by the Mini Nutritional Assessment test: what are the main factors? Nutrition. 2003; 19:767–771.
Article
Full Text Links
  • YMJ
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr