Clin Mol Hepatol.  2014 Sep;20(3):300-305. 10.3350/cmh.2014.20.3.300.

Gastrectomy for the treatment of refractory gastric ulceration after radioembolization with 90Y microspheres

• Yim SY
• Kim JD
• Jung JY
• Kim CH
• Seo YS
• Yim HJ
• Um SH
• Ryu HS
• Kim YH
• Kim CS
• Shin E

• KMID: 2069767
• DOI: http://doi.org/10.3350/cmh.2014.20.3.300

Abstract

Transcatheter arterial radioembolization (TARE) with Yttrium-90 (90Y)-labeled microspheres has an emerging role in treatment of patients with unresectable hepatocellular carcinoma. Although complication of TARE can be minimized by aggressive pre-evaluation angiography and preventive coiling of aberrant vessels, radioembolization-induced gastroduodenal ulcer can be irreversible and can be life-threatening. Treatment of radioembolization-induced gastric ulcer is challenging because there is a few reported cases and no consensus for management. We report a case of severe gastric ulceration with bleeding that eventually required surgery due to aberrant deposition of microspheres after TARE.

Keyword

Gastrectomy; Gastric ulcer; Hepatocellular carcinoma; Radioembolization; Yttrium-90

MeSH Terms

Aged
Carcinoma, Hepatocellular/*diagnosis/radiotherapy
Embolization, Therapeutic/*adverse effects
Gastrectomy
Gastrointestinal Hemorrhage/etiology
Gastroscopy
Humans
Liver Neoplasms/*diagnosis/radiotherapy
Magnetic Resonance Imaging
Male
*Microspheres
Radiopharmaceuticals/therapeutic use
Stomach/pathology
Stomach Ulcer/*etiology/surgery
Yttrium Radioisotopes/chemistry
Radiopharmaceuticals
Yttrium Radioisotopes