Clin Mol Hepatol.  2014 Sep;20(3):300-305. 10.3350/cmh.2014.20.3.300.

Gastrectomy for the treatment of refractory gastric ulceration after radioembolization with 90Y microspheres

Affiliations
  • 1Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. motet76@gmail.com
  • 2Department of Internal Medicine, Cheju Halla General Hospital, Jeju, Korea.
  • 3Department of Radiology, Korea University College of Medicine, Seoul, Korea.
  • 4Department of Surgery, Korea University College of Medicine, Seoul, Korea.
  • 5Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea.

Abstract

Transcatheter arterial radioembolization (TARE) with Yttrium-90 (90Y)-labeled microspheres has an emerging role in treatment of patients with unresectable hepatocellular carcinoma. Although complication of TARE can be minimized by aggressive pre-evaluation angiography and preventive coiling of aberrant vessels, radioembolization-induced gastroduodenal ulcer can be irreversible and can be life-threatening. Treatment of radioembolization-induced gastric ulcer is challenging because there is a few reported cases and no consensus for management. We report a case of severe gastric ulceration with bleeding that eventually required surgery due to aberrant deposition of microspheres after TARE.

Keyword

Gastrectomy; Gastric ulcer; Hepatocellular carcinoma; Radioembolization; Yttrium-90

MeSH Terms

Aged
Carcinoma, Hepatocellular/*diagnosis/radiotherapy
Embolization, Therapeutic/*adverse effects
Gastrectomy
Gastrointestinal Hemorrhage/etiology
Gastroscopy
Humans
Liver Neoplasms/*diagnosis/radiotherapy
Magnetic Resonance Imaging
Male
*Microspheres
Radiopharmaceuticals/therapeutic use
Stomach/pathology
Stomach Ulcer/*etiology/surgery
Yttrium Radioisotopes/chemistry
Radiopharmaceuticals
Yttrium Radioisotopes
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