J Korean Neurosurg Soc.  2011 Jul;50(1):45-47. 10.3340/jkns.2011.50.1.45.

Serious Blood-Brain Barrier Disruption after Coil Embolization of Unruptured Intracranial Aneurysm : Report of Two Cases and Role of Immediate Postembolization CT Scan

• Lee KK
• Kang DH
• Kim YS
• Park J

• KMID: 2066851
• DOI: http://doi.org/10.3340/jkns.2011.50.1.45

Abstract

Abnormal contrast enhancement on brain computed tomography (CT) scan after diagnostic or interventional angiography is not rare, and has known to be induced by temporary blood-brain barrier (BBB) disruption from contrast media. Furthermore, it has been regarded as clinically subtle, but reported to have no symptom or mild transient symptoms. However, we recently experienced two cases of serious BBB disruption during the acute period after coiling of an unruptured intracranial aneurysm. One patient presented with an unruptured paraclinoid internal carotid artery (ICA) aneurysm on the right and the other with an unruptured right supraclinoid ICA aneurysm. Both patients showed similar findings on immediate postembolization CT scan and clinical courses after coiling. Typical radiological, clinical characteristics of BBB disruption were described. In addition, the role of immediate postembolization CT scan are also discussed.

Keyword

Aneurysm; Blood-brain barrier; Coil; Embolization

MeSH Terms

Aneurysm
Angiography
Blood-Brain Barrier
Brain
Carotid Artery, Internal
Contrast Media
Humans
Intracranial Aneurysm
Contrast Media