J Korean Neurol Assoc.  1999 Sep;17(5):726-729.

A case of Neuro-Behcet's disease with CNS lesions confined to multiple cortical areas

• Lee JK
• Im JH
• Bang HJ
• Ryu JY
• Lee MJ

Abstract

We report a patient diagnosed with neuro-Behcet's disease showing multiple enhancing lesions on a brain MRI that were confined to the cerebral cortex without any involvement of other brain regions. The patient, a 30-year-old man, was admitted because of seizure attacks. He had the symptom triad of recurrent oral ulcer, genital ulcer, and uveitis. Neurologic symptoms included ataxia, dysarthria, and dementia which had progressed over several years. During the hospital course, he underwent a right hemicolectomy due to bowel perforation. A pathological examination showed multiple discrete ulcerations from the cecum to the mid-transverse colon, consistent with Behcet's colitis. A brain MRI revealed multiple small enhancing lesions distributed over wide areas of the cerebral cortex. To our knowledge, this pattern of lesion distribution has not yet been reported in neuro-Behcet's disease.

Keyword

Neuro-Behcet's disease; MRI; Multiple cortical lesions

MeSH Terms

Adult
Ataxia
Brain
Cecum
Cerebral Cortex
Colitis
Colon
Dementia
Dysarthria
Humans
Magnetic Resonance Imaging
Neurologic Manifestations
Oral Ulcer
Seizures
Ulcer
Uveitis