Korean J Thorac Cardiovasc Surg.
2000 Dec;33(12):982-987.
Extrapleural Pneumonectomy for Diffuse Malignant Mesothelioma: Report of four cases
- Affiliations
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- 1Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea.
- 2Department of Thoracic and Cardiovascular Surgery, Sanggye Paik Hospital, Inje University, College of Medicine Seoul, Korea.
- 3Department of Diagnostic Radiology, Sanggye Paik Hospital, Inje University, College of Medicine Seoul, Korea.
- 4Department of Internal Medicine, Sanggye Paik Hospital, Inje University, College of Medicine Seoul, Korea.
Abstract
- Diffuse malignant mesothelioma is a rare malignant tumor having poor prognosis. There is still no widely acceptable staging system of the disease and pathologic diagnosis is difficult. Although surgical treatment for diffuse malignant mesothelioma has been controversial, extrapleural peumonectomy in selected patients could prolong the survival when it was combined with adjuvant chemotherapy and radiation therapy. We experienced 4 cases of diffuse malignant mesothelioma for 7 years since 1992, they were treated with extrapleural pneumonectomy without early postoperative mortality. Three patients underwent adjuvant therapy after surgery; chemotherapy in two, and chemo-radiation therapy in one, but one patient could not receive adjuvant therapy because of postoperative complication of hypoxic brain damage due to cardiac torsion and empyema. In this article, we describe surgical experience of extrapleural pneumonectomy and discuss about the controversial points of the disease.
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