Korean J Thorac Cardiovasc Surg.  1999 Apr;32(4):341-346.

Valve Replacement in Children

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, School of Medicine, Keimyung University, Taegu, Korea.

Abstract

BACKGROUND: Thirty children ranging from 3 to 15 years of age underwent cardiac valve replacement at Dongsan Medical Center from 1982 to 1997. MATERIAL AND METHOD: There were 16 boys and 14 girls. The mean age was 12.1. The underlying pathological cause for valve replacement was congenital heart disease in 17 children and acquired heart disease in 13. The valve replaced was mitral in 15 children, aortic in 11, tricuspid in 3, and combined aortic and mitral in 1. Twenty-one mechanical and 10 tissue valves were placed: primary mechanical valve have been utilized since 1985. Eight of ten patients with tissue valves have had successful second valve replacements 4 to 11 years after the initial operation. RESULT: The operative mortality was 6.7%, but mortality was higher among patients less than 5 years of age and patients who had previous cardiac operations. Of the 28 operative survivors, 4 patients were lost to follow-up: the remaining patients were observed for a total of 2091 patient/months(mean 74.7 months, maximum 187 months). There was one late death from dilated cardiomyopathy after mitral valve replacement in 7 year-old patient with atrioventricular septal defect. After the operation, all patients with mechanical valves were placed on a strict anticoagulant regimen with Coumadin. The actuarial survival rate was 96% at the end of the follow-up. No instance of thromboembolism or major bleeding were observed in the survivors.
CONCLUSION
These results indicate that valve replacement can be performed with low mortality in children, and with satisfactory long-term survival.

Keyword

Child; Heart valve replacement

MeSH Terms

Cardiomyopathy, Dilated
Child*
Female
Follow-Up Studies
Heart Defects, Congenital
Heart Diseases
Heart Valves
Hemorrhage
Humans
Lost to Follow-Up
Mitral Valve
Mortality
Survival Rate
Survivors
Thromboembolism
Warfarin
Warfarin
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