Korean J Urol.  2012 Sep;53(9):614-618. 10.4111/kju.2012.53.9.614.

Efficacy of Holmium Laser Urethrotomy in Combination with Intralesional Triamcinolone in the Treatment of Anterior Urethral Stricture

• Kumar S
• Kapoor A
• Ganesamoni R
• Nanjappa B
• Sharma V
• Mete UK

• KMID: 2061699
• DOI: http://doi.org/10.4111/kju.2012.53.9.614

Abstract

PURPOSE
To evaluate the outcome of visual internal urethrotomy with a holmium:yttrium-aluminum-garnet laser along with intralesional triamcinolone injection.
MATERIALS AND METHODS
Patients with an anterior urethral stricture less than 3 cm in length were evaluated by clinical history, physical examination, uroflowmetry, and retrograde urethrogram preoperatively. All patients were treated with holmium laser urethrotomy and intralesional triamcinolone (80 mg) injection under general or regional anesthesia. An 18 F urethral catheter was placed for 5 days. All patients were followed up for 12 months postoperatively by history, uroflowmetry, and if required, retrograde urethrogram or urethroscopy every 3 months.
RESULTS
The mean age of the patients was 42.9 years (range, 14 to 70 years). The overall recurrence rate was 24%. The success rate in patients with strictures less than 1 cm in length was 95.8%, whereas that in patients with strictures of 1 to 3 cm in length was 57.7% (p=0.002). The outcome did not depend on age, duration of symptoms, etiology, or location of stricture.
CONCLUSIONS
Holmium laser urethrotomy with intralesional triamcinolone is a safe and effective minimally invasive therapeutic modality for urethral strictures. This procedure has an encouraging success rate, especially in those with stricture segments of less than 1 cm in length.

Keyword

Lasers; Laser therapy; Solid state; Triamcinolone acetonide; Urethral stricture

MeSH Terms

Anesthesia, Conduction
Constriction, Pathologic
Holmium
Humans
Laser Therapy
Lasers, Solid-State
Physical Examination
Recurrence
Triamcinolone
Triamcinolone Acetonide
Urethral Stricture
Urinary Catheters
Holmium
Triamcinolone
Triamcinolone Acetonide

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