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A Meta-Analysis of Association between Remdesivir and Mortality among Critically-Ill COVID-19 Patients

Razzack AA, Hassan SA, Reddy Pasya SK, Erasani G, Kumar S, Rocha-Castellanos DM, Lopez-Mendez A, Razzack SA

Background: The World Health Organization guidelines did not make a recommendation on use of remdesivir based on disease severity. Little is known regarding effectiveness of remdesivir in critically ill coronavirus...
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Development of a Unique Mouse Intervertebral Disc Degeneration Model Using a Simple Novel Tool

Baldia M, Mani S, Walter N, Kumar S, Srivastava A, Prabhu K

Study Design: Animal case control study. Purpose: To create a simple, reproducible disc degeneration model for mouse coccygeal vertebrae. Overview of Literature: Back pain due to disc degeneration is probably the...
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Clinical outcomes and technical description of unstented end to side pancreaticogastrostomy by small posterior gastrotomy

Bhoriwal SK, Kumar S, Deo S, Sharma J, Mishra A, Kumar N, Saikia J, Dhall K

Backgrounds/Aims: Morbidity following Whipple’s surgery largely depends upon the pancreatic stump anastomosis leak. Pancreaticogastrostomy is one of the techniques of pancreatic stump reconstruction and is described variously in the literature. Duct...
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Ventricular Arrhythmia Burden as a Marker of Success Following Catheter Ablation of Ventricular Arrhythmias in Patients with Structural Heart Disease

Bennett R, Turnbull S, Kotake Y, Campbell T, Kumar S

Background and Objectives: There is little emphasis on the efficacy of catheter ablation for ventricular arrhythmia (VA) when using VA burden reduction as a marker for success. We examined the...
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Morbidity Patterns among Menopausal Women in Rural Uttar Pradesh, India: A Cross-Sectional Study

Mathew DJ, Kumar S, Jain PK, Srivastava DK, Singh V, Krishnappa K

Objectives: The quality of life declines gradually as women enter menopause, owing to the various problems associated with estrogen deficiency and aging, which adds to their morbidities. This study aimed...
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Identification of potential candidate genes for lip and oral cavity cancer using network analysis

Mathavan S, Kue CS, Kumar S

Lip and oral cavity cancer, which can occur in any part of the mouth, is the 11th most common type of cancer worldwide. The major obstacles to patients’ survival are...
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Developmental toxicity of cadmium in infants and children: a review

Chandravanshi L, Shiv K, Kumar S

Several millions of people are exposed to cadmium worldwide due to natural and anthropogenic activities that led to their widespread distribution in the environment and have shown potential adverse effects...
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Prevention of epidural catheter migration: a comparative evaluation of two tunneling techniques

Gautam S, Agarwal A, Das PK, Khuba S, Kumar S

Background Epidural analgesia failure episodes can be reduced by catheter fixation techniques with a lower incidence of catheter migration. In this clinical study, we compared the roles of two epidural catheter...
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Updates in Ventricular Tachycardia Ablation

Campbell T, Bennett RG, Kotake Y, Kumar S

Sudden cardiac death (SCD) due to recurrent ventricular tachycardia is an important clinical sequela in patients with structural heart disease. As a result, ventricular tachycardia (VT) has emerged as a...
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Early Outcomes of Medial Pivot Total Knee Arthroplasty Compared to Posterior-Stabilized Design: A Randomized Controlled Trial

Kulshrestha V, Sood M, Kanade S, Kumar S, Datta B, Mittal G

Background: The indications for total knee arthroplasty (TKA) have been expanded to include younger, demanding patients. Some TKA patients expect a return to high-performance activities to restore optimum quality of...
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Ventricular Tachycardia Ablation in Non-ischemic Cardiomyopathy

Bhaskaran , De Silva K, Rao K, Campbell T, Trivic I, Bennett RG, Kizana E, Kumar S

Non-ischemic cardiomyopathies are a heterogeneous group of diseases of the myocardium that have a distinct proclivity to ventricular arrhythmias. Of these, ventricular tachycardias pose significant management challenges with the risk...
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Complex Obstetric Perineal Injury Reconstruction Using Antropyloric Valve Transposition

Kumar S, Medappil N, Singh SK, Chandra A

Despite significant advancements in the field of medicine, management of complex obstetric perineal injuries remains a challenge. Although several surgical techniques have been described, no techniques have provided satisfactory long-term...
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Prediction of hub genes of Alzheimer’s disease using a protein interaction network and functional enrichment analysis

Wee JJ, Kumar S

Alzheimer disease (AD) is a chronic, progressive brain disorder that slowly destroys affected individuals’ memory and reasoning faculties, and consequently, their ability to perform the simplest tasks. This study investigated...
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Unusual presentation of post-transplant lymphoproliferative disorder in renal transplant

Hanumaiah H, Sampathkumar K, Rajiv A, Kumar S, Kumar S, Desai H, Sampathkumar D

Background: Significantly increased malignancy risk exists in patients who undergo renal transplantation. Post-transplant lymphoproliferative disorder (PTLD) is a relatively rare but potentially fatal condition arising after renal transplant. While majority...
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Post renal transplant hyperparathyroidism: Indian experience

Sampathkumar D, Sampathkumar K, Rajiv A, Kumar S, Kumar S, Desai H, Hanumaiah H

Background: Progressive chronic kidney disease (CKD) results in secondary hyperparathyroidism (SHPT). After a successful renal transplant, theoretically SHPT should rapidly regress. But residual parathyroid overactivity may persist. Indian reports of...
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Clinical characteristics and outcomes of critically Ill patients with COVID-19 in Northeast Ohio: low mortality and length of stay

Fadel FA, Al-Jaghbeer M, Kumar S, Griffiths L, Wang X, Han X, Burton R

Background: Published coronavirus disease 2019 (COVID-19) reports suggest higher mortality with increasing age and comorbidities. Our study describes the clinical characteristics and outcomes for all intensive care unit (ICU) patients...
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Outcomes of Endoscopic Management among Patients with Bile Leak of Various Etiologies at a Tertiary Care Center

Giri S, Sundaram S, Darak H, Kumar S, Bhatia S

Background/Aims: Bile leak is a common complication of cholecystectomy, and it is also observed in other conditions such as ruptured liver abscess, hydatid cyst, and trauma. Endoscopic retrograde cholangiopancreatography (ERCP)...
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Major enteropathogens in humans, domestic animals, and environmental soil samples from the same locality: prevalence and transmission considerations in coastal Odisha, India

Shrivastava AK, Mohakud NK, Panda S, Patra SD, Kumar S, Sahu PS

Objectives: Regions with limited sanitation facilities have higher rates of infections with various enteric pathogens. It is therefore important to identify different hosts and their relative contribution to pathogen shedding...
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New Onset Obsessive Compulsive Disorder Following High Frequency Repetitive Transcranial Magnetic Stimulation over Left Dorsolateral Prefrontal Cortex for Treatment of Negative Symptoms in a Patient with Schizophrenia

Garg H, Kumar S, Singh S, Kumar N, Verma R

Obsessive-compulsive symptoms and/or obsessive-compulsive disorders (OCD) are frequently comorbid with schizophrenia, though the exact clinical and etiological relationship between them is poorly understood. Here we describe a case that, to...
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Versatile midfacial degloving approach in oral and maxillofacial surgery

Pangarikar A, G U, Parab P, Kumar S, M.V. D

OBJECTIVES: Oral and maxillofacial surgeons must gain mastery of various approaches to the midface due to the increasing incidence, complexity, and severity of presenting midfacial fractures. Unlike in the case...
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