J Korean Acad Periodontol.  2002 Jun;32(2):339-350. 10.5051/jkape.2002.32.2.339.

Histopathologic Study of the Effect of two Bovine Bone Powder on Healing of Extraction Socket of Dogs

• Lee SH
• Lim SB
• Chung CH
• Lee CH

• KMID: 2057045
• DOI: http://doi.org/10.5051/jkape.2002.32.2.339

Abstract

Recently the esthetic demands of clinicians and patients made the surgeon try to regenerate bone defects and gingival tissue after extraction. For that, many surgical methods were used and socket preservation have been evaluated simple, effective and good prognosis in the implant placement. Bone grafting was one of the methods for socket preservation. This study was to evaluate the histologic view of the effects on healing of the extraction sockets when deproteinized bovine bone mineral and tetracycline coated deproteinized bovine bone mineral was implanted 1. In control group, at 4 weeks after implantation, the extraction sockets were filled with connective tissue. And after 8 weeks, osteoblasts were observed in newly formed trabecular among the fibrous connective tissue in the extraction sockets. 2. In experimental 1 group, there was connective tissue and new bone trabecular around newly formed woven bone at 4 weeks. And many osteoblasts were observed in various direction at 8 weeks. 3. In experimental 2 group, there was a lot of new bone made around the bone powder after 4 weeks, and the thicker bone trabecular, lamellar bone and irregular osteoblasts arrangement were observed at 8 weeks. From the results of this study, tetracycline coated BBP would be better than the other groups in the lamellar bone formation and be faster in the bone formation rate.

MeSH Terms

Animals
Bone Transplantation
Connective Tissue
Dogs*
Humans
Osteoblasts
Osteogenesis
Prognosis
Tetracycline
Tetracycline