Mycobiology.  2009 Sep;37(3):243-246. 10.4489/MYCO.2009.37.3.243.

In vitro Antifungal Activity of Limonene against Trichophyton rubrum

Affiliations
  • 1Division of Cell Biology, Medical College, Konyang University, TaeJeon City, Korea. hychee@konyang.ac.kr
  • 2Department of Medical Beauty, Konayng University, Nonsan City, Korea.

Abstract

In this study, the antifungal activities of limonene against Trichophyton rubrum were evaluated via broth microdilution and vapor contact assays. In both assays, limonene was shown to exert a potent antifungal effect against T. rubrum. The volatile vapor of limonene at concentrations above 1 microl/800 ml air space strongly inhibited the growth of T. rubrum. The MIC value was 0.5% v/v in the broth microdilution assay. The antifungal activity of limonene against T. rubrum was characterized as a fungicidal effect.

Keyword

Antifungal activities; Limonene; Trichophyton rubrum

MeSH Terms

Cyclohexenes
Terpenes
Trichophyton
Cyclohexenes
Terpenes
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