Mycobiology.
2009 Mar;37(1):37-42. 10.4489/MYCO.2009.37.1.037.
Comparative Effects of Oyster Mushrooms on Lipid Profile, Liver and Kidney Function in Hypercholesterolemic Rats
- Affiliations
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- 1Department of Biology, University of Incheon, Incheon 402-749, Korea. tslee@incheon.ac.kr
- 2Department of Botany, Jahangirnagar University, Savar, Dkaka-1342, Bangladesh.
- 3National Mushroom Development and Extension Centre, Savar, Dhaka, Bangladesh.
- 4Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dkaka-1342, Bangladesh.
- 5Department of Zoology, Jahangirnagar University, Savar, Dkaka-1342, Bangladesh.
- 6Department of Life Science, University of Seoul, Seoul 130-743, Korea.
- 7Department of Biology, Dongguk University, Seoul 100-715, Korea.
- KMID: 2053000
- DOI: http://doi.org/10.4489/MYCO.2009.37.1.037
Abstract
- Comparative effects of oyster mushrooms on plasma and fecal lipid profiles and on liver and kidney function were evaluated in hyper and normocholesterolemic rats. Feeding of hypercholesterolemic rats a 5% powder of oyster mushrooms (Pleurotus ostreatus, P. sajor-caju and P. florida) reduced the plasma total cholesterol level by 37%, 21% and 16%, respectively and reduced the triglyceride level by 45%, 24% and 14%, respectively. LDL/HDL ratio decreased by 64%, 45% and 41% for P. sajor-caju, P. ostreatus and P. florida fed rats, respectively. Mushroom feeding also reduced body weight in hypercholesterolemic rats. However, it had no adverse effect on plasma bilirubin, creatinin and urea nitrogen level. Mushroom feeding also increased the total lipid and cholesterol excretion in the feces. The present study reveals that feeding of 5% oyster mushroom powder does not have detrimental effects on the liver and kidneys rather may provide health benefits for the cardiovascular-related complication by decreasing the atherogenic lipid profiles.
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