Nucl Med Mol Imaging.  2012 Jun;46(2):134-137.

Giant Cell Tumor Pulmonary Metastases Mimic Primary Malignant Pulmonary Nodules on 18F-FDG PET/CT

Affiliations
  • 1Department of Nuclear Medicine, Brandon Regional Health Centre, 150 McTavish Ave E, Brandon, MB, R7A 2B3, Canada. makisw79@yahoo.com
  • 2Department of Nuclear Medicine, Royal Victoria Hospital, McGill University Health Centre, 687 Pine Ave West, M2, Montreal, QC, H3A 1A1, Canada.
  • 3Department of Pathology, Montreal General Hospital, McGill University Health Centre, 1650 Avenue Cedar, D3-257, Montreal, QC, H3G 1A4, Canada.

Abstract

A 59-year-old man with a 30-year history of multiple recurrences of a giant cell tumor (GCT) of the left knee was referred for an 18F-FDG PET/CT to evaluate a solitary pulmonary nodule. The nodule was mildly FDG-avid, raising suspicion of malignancy. It was excised and histologically proven to be a GCT pulmonary metastasis. A follow-up PET/CT done 2 years later revealed a new, larger lung mass that was more intensely FDG-avid, but of the same histology. This rare report highlights a pitfall in the evaluation of solitary pulmonary lesions by 18F-FDG PET/CT in patients with GCT of the bone.

Keyword

Giant cell tumor; GCT; Pulmonary metastases; FDG; PET/CT

MeSH Terms

Fluorodeoxyglucose F18
Follow-Up Studies
Giant Cell Tumors
Giant Cells
Humans
Hydrazines
Knee
Lung
Middle Aged
Neoplasm Metastasis
Recurrence
Solitary Pulmonary Nodule
Fluorodeoxyglucose F18
Hydrazines
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