Tuberc Respir Dis.  2006 Jun;60(6):673-677. 10.4046/trd.2006.60.6.673.

A Case of Monophasic Fibrous Synovial Sarcoma Confirmed Primary Pulmonary Origin by 18F-FDG PET/CT

• Lee EA
• Lee DY
• Kwag HJ
• Kim MK
• Oh TY
• Lim SY
• Lim SY

• KMID: 1630806
• DOI: http://doi.org/10.4046/trd.2006.60.6.673

Abstract

Most malignant mesenchymal tumors of the lung are metastases of a primary tumor from elsewhere in the body. A primary pulmonary synovial sarcoma is a very rare neoplasm that accounts for approximately 10% of soft tissue sarcomas and makes up only 0.5% of all primary lung malignancies. We report a case of a primary pulmonary synovial sarcoma in a 60-year old woman. In this case, a lung metastasis was excluded using 18F-FDG PET /CT imaging.

Keyword

Primary pulmonary synovial sarcoma; FDG PET/CT

MeSH Terms

Female
Fluorodeoxyglucose F18*
Humans
Lung
Middle Aged
Neoplasm Metastasis
Positron-Emission Tomography and Computed Tomography*
Sarcoma
Sarcoma, Synovial*
Fluorodeoxyglucose F18

Figure

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  Figure 1 (A) Chest radiograph shows right lower lobe mass. (B) On chest CT scan, 5×4cm sized well demarcated and highly enhancing mass was noted in right lower lobe.

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  Figure 2 (A) FDG PET coronal image: FDG PET scan reveals increased FDG uptake foci in right lower lobe (peak SUV=3.7). (B) FDG PET fused coronal image: fusion PET demonstrated mild hypermetabolic mass in right lower lobe.

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  Figure 3 The cut surface of the resected lung shows a relatively well demarcated pale yellow tan solid mass with fish flesh-like appearance. The bronchial tree is grossly intact.

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  Figure 4 Light microscopic finding shows that tumor is composed of highly cellular spindle cells with long intersecting fascicular arrangement and mild to moderate atypism (H&E, ×400).

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  Figure 5 The results of immunohistochemical stains. The tumor cells are completely negative for smooth muscle actin (A; ×400) and CD34 (B; ×400). The majority of tumor cells show strong and diffuse positive reaction for bcl-2 (C; ×400) and vimentin (D; ×400).

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