Nucl Med Mol Imaging.  2008 Feb;42(1):79-80.

Non-specific Inflammatory Disease Showed Abnormal FDG Uptake in Lower Extremities

• Chun KA
• Kong EJ
• Cho IH
• Hong YH
• Lee CK

Abstract

Including malignancy, various disease can show abnormal uptake in bone marrow.1,2) We report a case of non-specific inflammatory FDG uptake in bone marrow mimicking malignancy. A 35-year old woman with fever of unknown origin (FUO) underwent 18F-FDG PET/CT to find out fever focus and unknown malignancy. 18F-FDG was injected and imaged 1hr after injection with Discovery ST (GE, USA). 18F-FDG PET/CT whole body image showed abnormal uptake in lower extremities (Fig. 1). MRI and biopsy was also done in the sites of abnormal uptake. PET and MRI suspect malignancy (Fig. 2, 3), but biopsy result was non-specific inflammatory process (Fig. 4). The patient was improved her clinical condition after antibiotics therapy.

Keyword

18F-FDG; FUO; bone marrow

MeSH Terms

Anti-Bacterial Agents
Biopsy
Body Image
Bone Marrow
Female
Fever
Fever of Unknown Origin
Fluorodeoxyglucose F18
Humans
Lower Extremity
Anti-Bacterial Agents
Fluorodeoxyglucose F18