Yeungnam Univ J Med.  2012 Dec;29(2):145-149. 10.12701/yujm.2012.29.2.145.

A Case of Chronic Renal Failure Associated with Systemic Capillary Leak Syndrome

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. imsejoong@daum.net
  • 2Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
  • 3Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 4Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea.

Abstract

Systemic capillary leak syndrome (SCLS) is an unusual entity characterized by hypovolemic shock, hemoconcentration, and hypo-albuminemia associated with paraproteinemia as a result of marked capillary hyperpermeability. Complications of this syndrome can include compartment syndromes, pulmonary edema, thrombosis, and acute kidney injury. This paper reports a case of severe SCLS accompanied by acute tubular necrosis caused by hypoperfusion and myoglobinuria secondary to rhabdomyolysis, which resulted in chronic kidney disease that necessitated hemodialysis. However, there have been rare data of residual end-organ damage after acute attacks in Korea. Therefore, this paper reports a case of complicated SCLS enough to hemodialysis and that developed into chronic kidney disease.

Keyword

Acute tubular necrosis; Rhabdomyolysis; Systemic capillary leak syndrome; Chronic renal failure

MeSH Terms

Acute Kidney Injury
Capillaries
Capillary Leak Syndrome
Compartment Syndromes
Kidney Failure, Chronic
Korea
Myoglobinuria
Necrosis
Paraproteinemias
Pulmonary Edema
Renal Dialysis
Renal Insufficiency, Chronic
Rhabdomyolysis
Shock
Thrombosis
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