Clin Pediatr Hematol Oncol.
2013 Apr;20(1):59-61.
Ecthyma Gangrenosum Caused by Klebsiella Pneumoniae in Immunocompromised Patient Associated with Severe Aplastic Anemia
- Affiliations
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- 1Department of Pediatrics, Chonbuk National University Medical School, Jeonju, Korea. hwaph@jbnu.ac.kr
- 2Research Institute of Clinical Medicine, Chonbuk National University Medical School, Jeonju, Korea.
Abstract
- Ecthyma gangrenosum (EG) is a skin infection that is classically associated with Pseudomonas aeruginosa septicemia in immunocompromised patients with severe neutropenia. Other bacterial, viral, and fungal pathogens also have been implicated in EG. EG is rare condition with characteristic clinical appearance of red macule that progresses to a central area presenting a necrotic black or gray-black eschar with surrounding erythema. The skin lesions usually occur in the gluteal and perineal regions or extremities and widespread over the body. Although the usual outcome is poor, early recognition and appropriate systemic antibiotic treatment can lead to successful outcome. Therefore, we describe a case of EG associated with Klebsiella pneimoniae in a 15-year-old patient with severe aplastic anemia and review the literature.
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