Clin Pediatr Hematol Oncol.
2006 Apr;13(1):55-59.
A Case of Concurrent Acute Myelogenous Leukemia and Retroperitoneal Teratoma in an Infant
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Pusan National University, Busan, Korea. limyt@pusan.ac.kr
- 2Department of Pathology, College of Medicine, Pusan National University, Busan, Korea.
- 3Department of Laboratory Medicine, College of Medicine, Pusan National University, Busan, Korea.
Abstract
- Most hematologic malignancies occurring in a patient with a malignant solid tumor are secondary leukemia developing as complications after chemotherapy or radiotherapy. On the other hand, it is very rare for a solid tumor and leukemia to occur simultaneously in a patient without antecedent chemotherapy or radiotherapy. It may be possible that leukemia occurs concurrently with a germ cell tumor because hematopoietic cells and germ cells originate from the yolk sac. In a 3-month-old female diagnosed with acute myelogenous leukemia (AML), a retroperitoneal mature teratoma was found incidentally during the induction chemotherapy. We describe this rare case of concurrent AML and retroperitoneal teratoma in an infant.
