Chonnam Med J.  2008 Aug;44(2):109-112. 10.4068/cmj.2008.44.2.109.

Isolated Oculomotor Nerve Palsy due to Non-Hodgkin's Lymphoma Demonstrated by Serial MRI

• Choi SM
• Kim JT
• Lee SH
• Park MS
• Kim BC
• Kim MK
• Cho KH

• KMID: 2045759
• DOI: http://doi.org/10.4068/cmj.2008.44.2.109

Abstract

We present a 34-yr-old lymphoma patient who developed isolated oculomotor nerve palsy. Initial brain MRI and cerebrospinal fluid (CSF) findings were negative, but follow-up brain MRI showed a mass lesion in the cavernous sinus which encroached on the oculomotor nerve. This case suggest that, when isolated oculomotor nerve palsy develops in a patient with lymphoma, cavernous sinus involvement should be considered. Although initial brain imaging and CSF findings were negative, the follow-up imaging should be performed to detect the cause of the neurologic sign.

Keyword

Oculomotor nerve palsy; Non-Hodgkin's lymphoma

MeSH Terms

Brain
Cavernous Sinus
Follow-Up Studies
Humans
Lymphoma
Lymphoma, Non-Hodgkin
Neuroimaging
Neurologic Manifestations
Oculomotor Nerve
Oculomotor Nerve Diseases

Figure

• 

  Fig. 1 Initial brain MRI findings at the level of the brain stem and CT angiography on the first visit. Neither parenchymal mass lesion nor aneurysm were found. (A) Axial T2-weighted image, (B) Axial gadolinium-enhanced T1-weighted image, (C) Coronal gadoliniumenhanced T1-weighted image, (D) CT angiography.

• 

  Fig. 2 Follow-up findings of brain MRI at 2 weeks later. A slightly enhancing mass (white arrows on A and B) around the left internal carotid artery and the oculomotor nerve in cavernous sinus was found. (A) Coronal T2-weighted image, (B) Axial gadolinium-enhanced T1-weighted image.

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