Clin Exp Reprod Med.
2011 Jun;38(2):115-118. 10.5653/cerm.2011.38.2.115.
A large advanced seminoma in an older woman with androgen insensitivity syndrome
- Affiliations
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- 1Department of Family Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- 2Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. chnkim@amc.seoul.kr
- 3Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- KMID: 2045705
- DOI: http://doi.org/10.5653/cerm.2011.38.2.115
Abstract
- A 58-year-old woman who presented with inguinal hernia for the first time was diagnosed as seminoma and complete androgen insensitivity syndrome (CAIS). The patient received a late diagnosis, and therefore she could not take a proper management. CAIS is a rare X-linked recessive disease with an XY karyotype that is caused by androgen receptor defects. It usually present with primary amenorrhea or inguinal hernia. The risk of malignant transformation of undescended testis increases with age, thus gonadectomy should be performed after puberty. We present a case of large advanced seminoma in a woman with CAIS who was neglected and diagnosed lately.
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