Clin Exp Reprod Med.  2011 Jun;38(2):93-97. 10.5653/cerm.2011.38.2.93.

Age specific serum anti-Mullerian hormone levels in 1,298 Korean women with regular menstruation

• Yoo JH
• Kim HO
• Cha SW
• Park CW
• Yang KM
• Song IO
• Koong MK
• Kang IS

• KMID: 2045701
• DOI: http://doi.org/10.5653/cerm.2011.38.2.93

Abstract

OBJECTIVE
To determine the age specific serum anti-Mullerian hormone (AMH) reference values in Korean women with regular menstruation.
METHODS
Between May, 2010 and January, 2011, the serum AMH levels were evaluated in a total of 1,298 women who have regular menstrual cycles aged between 20 and 50 years. Women were classified into 6 categories by age: 20-31 years, 32-34 years, 35-37 years, 38-40 years, 41-43 years, above 43 years. Measurement of serum AMH was measured by commercial enzyme-linked immunoassay.
RESULTS
The serum AMH levels correlated negatively with age. The median AMH level of each age group was 4.20 ng/mL, 3.70 ng/mL, 2.60 ng/mL, 1.50 ng/mL, 1.30 ng/mL, and 0.60 ng/mL, respectively. The AMH values in the lower 5th percentile of each age group were 1.19 ng/mL, 0.60 ng/mL, 0.42 ng/mL, 0.27 ng/mL, 0.14 ng/mL, and 0.10 ng/mL, respectively.
CONCLUSION
This study determined reference values of serum AMH in Korean women with regular menstruation. These values can be applied to clinical evaluation and treatment of infertile women.

Keyword

Anti-Mullerian Hormone; Ovarian Reserve; Korean; Human

MeSH Terms

Aged
Anti-Mullerian Hormone
Female
Humans
Menstrual Cycle
Menstruation
Reference Values
Anti-Mullerian Hormone