J Korean Neurosurg Soc.  2002 Dec;32(6):564-569.

The Factors Affecting Enlargement of Spontaneous Intracerebral Hemorrhage

• Kim HY
• Mok JH
• Park HK
• Lee KC
• Park YS
• Lee YB

Abstract

OBJECTIVE
The goal of this study is to evaluate the incidence and factors of hematoma enlargement in patients with spontaneous intracerebral hemorrhage(ICH).
METHODS
We analyzed 149 cases with spontaneous ICH who underwent computerized tomography (CT) scans from January, 1995 to December, 1998. The clinical characteristics, past medical history, laboratory findings, time intervals between onset of ICH and CT scan, CT findings and results of treatment were reviewed.
RESULTS
Of the total 149 patients, 28(18.8%) had hematoma enlargement, of whom 24(85.7%) underwent a first CT scan within 3 hours after onset of ICH. The incidence of hematoma enlargement significantly decreased in patients who had CT scans 3 hours later after attack. Age, sex, and site of hematoma were not related to hematoma enlargement. Patients with an irregularly shaped hematoma, inhomogenous hematoma and large hematoma had a high risk of hematoma enlargement. Hematoma enlargement was associated with a poor clinical outcome and high mortality(46.7%).
CONCLUSION
Patients admitted to a hospital within 3 hours of onset of ICH, and patients with inhomogenous hematoma on CT scan, irregularly shaped hematoma, or large hematoma should be closely observed for hematoma enlargement.

Keyword

Hematoma enlargement; Intracerebral hemorrhage; Factors

MeSH Terms

Cerebral Hemorrhage*
Hematoma
Humans
Incidence
Tomography, X-Ray Computed