J Korean Soc Plast Reconstr Surg.  2007 Jul;34(4):494-496.

Malignant Peripheral Nerve Sheath Tumor of Scalp

Affiliations
  • 1Department of Plastic Surgery, College of Medicine, The Catholic University of Korea, Gyeonggi, Korea. yjkim@hfh.cuk.ac.kr
  • 2Department of Pathology, College of Medicine, The Catholic University of Korea, Gyeonggi, Korea.

Abstract

PURPOSE: Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms, usually arising from somatic soft tissues or peripheral nerves. Primary MPNST of the scalp is extremely rare. The case is being reported for its rarity.
METHODS
A 53-year-old female was presented with a scalp mass on vertex area. The tumor was localized in scalp skin and did not invade underlying periosteum or skull and treated with complete surgical excision followed by adjuvant chemotherapy and radiotherapy.
RESULTS
Histologically, the tumor showed malignant spindle cells with focal S-100 positivity on immunohistochemistry and a diagnosis of MPNST was made.
CONCLUSION
Authors experienced a rare case of primary scalp MPNST and report the case.

Keyword

Malignant peripheral nerve sheath tumor (MPNST); Soft tissue sarcoma; Neurofibrosarcoma; Neurofibroma; Scalp mass

MeSH Terms

Chemotherapy, Adjuvant
Diagnosis
Female
Humans
Immunohistochemistry
Middle Aged
Neurilemmoma
Neurofibroma
Neurofibrosarcoma
Periosteum
Peripheral Nerves*
Radiotherapy
Sarcoma
Scalp*
Skin
Skull
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