Korean J Dermatol.  1988 Aug;26(4):560-564.

A Case of Generalized Perforating Granuloma Annulare

• Hong KT
• Lee KH
• Park CI

Abstract

Generalized perforating granuloma annulare is a rare variant of granuloma. annulare, which was first described by Duncan et al 1) in 1973. A 21-year-old female had hundreds of 3 to 5mm papules over the whole body, which were mainly distributed in the extremities and trunk since three months ago. Individual papules developed a central umbilication with a peripheral collarette of scale. Histopathologic examination showed an epidermal perforation and transepidermal elimination of necrobiotic material. The epidermal perforation communicated with areas of necrobiotic collagen surrounded by palisading granulorna in the dermis. We treated her with oral prednisolone and dapsone, but there was no clinical improvement.

Keyword

Granuloma annulare; Generalized perforating; Transepidermal elimination

MeSH Terms

Collagen
Dapsone
Dermis
Extremities
Female
Granuloma Annulare*
Granuloma*
Humans
Prednisolone
Young Adult
Collagen
Dapsone
Prednisolone