Korean J Perinatol.  2007 Mar;18(1):75-79.

A Case of Neonatal Jaundice due to Anti-Jk(b)

Affiliations
  • 1Department of Pediatrics, Hospital of Konkuk University, Seoul, Korea. kmh@kuh.ac.kr
  • 2Department of Laboratory Medicine, Hospital of Konkuk University, Seoul, Korea.

Abstract

The Kidd (Jk) system is one of the most important blood group systems in transfusion medicine due to immediate or delayed hemolytic transfusion reactions as well as hemolytic disease of newborn (HDN). We experienced a case of jaundice and hemolytic anemia in a newborn due to anti-Jk(b) incompatibility appearing within the first 24 hours of life. The infant's direct and indirect antiglobulin tests were positive. There were no ABO and Rh (D) incompatibilities between the mother and the baby. Direct Coomb's IgG was strongly positive but C3d was negative. We started the exchange transfusion with the whole blood and had a favorable outcome. We report this case with a brief review of relevant literature.

Keyword

Anti-Jk(b); Hemolytic disease of newborn; Exchange transfusion

MeSH Terms

Anemia, Hemolytic
Blood Group Incompatibility
Coombs Test
Erythroblastosis, Fetal
Humans
Immunoglobulin G
Infant, Newborn
Jaundice
Jaundice, Neonatal*
Mothers
Transfusion Medicine
Immunoglobulin G
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